Characterization of peptides and proteins involved in the reproduction and protection of gametes in the cephalopod Sepia officinalis-Analysis of neuropeptidome, peptidome and secretome of genital apparatus.
Approaches: Transcriptomics (next-generation Sequencing) - peptidomics – Proteomics (HPLC purification, SDS page, identification by mass spectrometry) - Functional testing (toxicity, antibacterial, myotropic…).
C. Zatylny-Gaudin, B. Bernay, B. Zanuttini, J. Leprince, H. Vaudry, J. Henry, Characterization of a novel LFRFamide neuropeptide in the cephalopod Sepia officinalis., Peptides. 31 (2010) 207–14.
J. Enault, C. Zatylny-Gaudin, B. Bernay, B. Lefranc, J. Leprince, M. Baudy-Floc’h, et al., A Complex Set of Sex Pheromones Identified in the Cuttlefish Sepia officinalis, PLoS One. 7 (2012) e46531.
L. Bigot, C. Zatylny-Gaudin, F. Rodet, B. Bernay, P. Boudry, P. Favrel, Characterization of GnRH-related peptides from the Pacific oyster Crassostrea gigas., Peptides. 34 (2012) 303–10.
J. Henry, V. Cornet, B. Bernay, C. Zatylny-gaudin, Peptides Identification and expression of two oxytocin/vasopressin-related peptides in the cuttlefish Sepia officinalis, Peptides. 46 (2013) 159–166.
C. Zatylny-Gaudin and P. Favrel, Diversity of the RFamide Peptide Family in Mollusks.,Front Endocrinol., 2014);5:178